How would one programmatically stop an app from reading computer files?

In a language like Python for scripting, how would you stop an app from having access to reading computer files, especially sensitive system-level ones?

Edit: To be clear, I mean set permissions for that app to not have access to computer files, even after the script is done running (setting permissions).

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You should run your python script as a non-privileged user and read a file after validating the access

# check readability of the path  if os.access("file.txt", os.R_OK):       # open txt file as file      with open("file.tx") as file:          return file.read()  
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